Climate change-driven shifts in distribution and abundance are documented in many species. However, in order to better predict species responses, managers are seeking to understand the mechanisms that are driving these changes, including any thresholds that might soon be crossed. We leveraged the research that has already been supported by the Northeast Climate Adaptation Science Center (NE CASC) and its partners and used the latest modeling techniques combined with robust field data to examine the impact of specific climate variables, land use change, and species interactions on the future distribution and abundance of species of conservation concern. Moreover, we documented biological thresholds related to climate variability and change for critical species in the Northeastern and Midwestern U.S. Our objectives were to identify the primary drivers (e.g